Hina-Multiple Sclerosis-(Israel)

Name: Hina
Sex: Female
Nationality: Israeli
Age: 47Y
Diagnosis: Multiple Sclerosis
Discharge Date: 2017/05/01

Before treatment:
The patient felt weak in her legs 18 years ago and she was diagnosed with multiple sclerosis. She did many treatments but her disease recurrently attacked many times. She began to use Tysabri 10 years ago and her condition became better. In June 2009 her condition got worse again and she did steroid treatments three times  in 1 year. She began to use Fingolimod from January 2013 but her condition still got worse and she had problems with her urination function. She began to use a walker in April 2014 and her condition became worse in June 2015 when she could barely walk. At present she is unable to sit up, stand or walk and it is hard for her to turn over.
Her spirit and diet are normal, she does not sleep well and she has frequency of urination.

Admission PE:
Bp: 110/68mmHg, Hr: 75/min, body temperature: 36.7 degrees. Nutrition status is normal with normal physical development. There was no skin damage or bleeding spots, no oral mucosa congestion  and  no tonsil swelling. The chest development was normal, respiratory sounds in both lungs were clear and with no moist rales. The heart beat is powerful with regular cardiac rhythm and no obvious murmur in the valves. The abdomen was soft and flat with no masses or tenderness. Liver and spleen were normal by touch and there was no edema of the legs.

Nervous System Examination:
Patient was alert and her mental status was good with clear speech and her orientation, memory and calculation abilities were normal. Both pupils were equal in size and round, diameter of 3.0 mm, react well to light and the eyeballs can move freely. Her eyesight was normal by gross measure with no nystagmus, no diplopia or visual field loss. Bilateral forehead wrinkle is symmetrical and the bilateral nasolabial groove depth is same. She could make her tongue extend out normally, there was no tongue muscle atrophy, showing teeth is normal, the uvula was in middle position and the soft palate can life normally. Her neck could move freely and the shrug ability was normal. The  muscle power of the arms was 4 degrees. The right leg muscle power was 1+ degree, left leg muscle power was 2 degrees. The  muscle tone of the arms were normal, leg muscle tone was increased. The arms biceps reflex was normal, radial periosteal reflex was normal. The  patellar tendon reflex of the legs was active and the abdomen reflex could not be induced by examination. Bilateral palm-jaw reflex was negative, the Hoffmann sign of both sides were negative and the Babinski sign was positive. The ankle clonus was negative and her leg sensory test was decreased. She could perform the finger to nose test, finger opposite movement and fast alternate movement normally. She could not perform the  heel-knee-tibia test because of weakness. She could not do the examination of Romberg's sign and the meningeal irritation sign was negative.

Treatment:
After the admission she received 3  nerve regeneration treatments (neural stem cells and mesenchymal stem cells) to repair her damaged nerves, replace dead nerves, nourish nerves, regulate her immune system and improve blood circulation. This was done with rehabilitation training.     

Post-treatment:
After 14 days treatment she could raise her legs better, her grip power was increased, she could do fine movement better and the muscle power of her legs was increased 30%. She could now do dorsiflexion and planter flexion better, she could sit up and stand by herself and she could walk 20 meters.

 

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